Health Outcomes, Epidemiology and Biostatistics Consulting

Perisphere RWE Mission

We make scientific discoveries and improve health outcomes by applying advanced epidemiology and statistical tools to generate real-world evidence.

Pharmacoepidemiology Expertise

  • Over 20 years experience generating real-world evidence (RWE).
  • Government experience – Acting Chief Science Officer for the Centers for Disease Control and Prevention (CDC).
  • Analyzing large claims datasets for FDA filings and regulatory requirements.
  • Implementing and leading data coordinating centers.
  • Member and chair of guideline and Scientific Statement committees.
  • Over 700 peer-reviewed publications in top medical journals (cited >100,000).

We Move Research
Beyond Publications

  • Primary data collection
  • Advanced data analytics
  • Cost-effectiveness analyses
  • Guideline implementation
  • Policy modeling
  • Engagement with key opinion leaders
  • Engagement with policy makers

Project Examples

Staging and clean room: Constructs designed to facilitate transparency and reduce bias in comparative analyses of real-world data.

Pragmatic considerations for negative control outcome studies to guide non-randomized comparative analyses: A narrative review.

Lipid-Lowering Therapy Use and Intensification Among United States Veterans Following Myocardial Infarction or Coronary Revascularization

Development of algorithms for identifying fatal cardiovascular disease in Medicare claims.

Comparative effects of biologics on cardiovascular risk among older patients with rheumatoid arthritis

Why Choose Perisphere RWE

Collaborative, engaging leaders as partners

Innovative, using advanced scientific methods

Productive, achieving high scientific productivity

Impactful, disseminating broadly through publications